Suresh Jaiswal, Bijay Subedi, Ashmita Sapkota, Pushpa Sharma, Manisha Timilsina, Maheshwor Timilsina, Bishnu Raj Tiwari,
Volume 18, Issue 1 (Jan-Feb 2024)
Abstract
Background: Intestinal infections with Helicobacter pylori mainly occur during childhood. If contracted, these infections may cause chronic gastritis, frequently leading to peptic ulcer disease in later life. This study aims to detect the prevalence of H. pylori infections in patients with active gastritis.
Methods: The study included 150 participants who were consuming daily anti-gastritis drugs to reduce the gas and were considered active gastritis patients and were recruited from Lekhnath 12, now known as Pokhara metropolitan-30, from May 2018 to March 2019. They were screened for H. pylori antibodies for detection of infection by the immunochromatographic rapid detection kit, and the data were analyzed using SPSS 2016.
Results: Serum anti-Helicobacter pylori antibodies were used to detect the presence of Helicobacter pylori in these participants. Among the 150 participants, 54 were males (36%) and 96 were females (64%). The results showed that 47 (31.3%) of the patients were positive for anti-Helicobacter pylori test. The age group 30 to 40 had the highest prevalence of 21 (14.0%). Using public water showed the highest prevalence with a P value of 0.04.
Conclusion: There should be an additional aspect required for the diagnosis and treatment of gastritis, which is the healthcare providers' and patients' awareness of the cause and most efficient treatments for this medical condition. Using only anti-gastritis drugs is not sufficient; treatment against Helicobacter pylori requires the right pathway of treatment by the use of several antibiotics.
Neema Tiwari , Richa Sharma , Prachi Saxena ,
Volume 19, Issue 4 (Jul-Aug 2025)
Abstract
Background: Nucleated red blood cells (nRBCs) are immature erythrocytes whose production is thought to be driven primarily by the interplay of hypoxia and erythropoietin synthesis. Neonatal sepsis is classified as early-onset (occurring within the first 24 hours of life) or late-onset (Occurring after 48-72 hours). The aim of this study was to analyze the cause for the presence of nRBCs in the peripheral blood of neonates sent for routine workup in the Hematology Laboratory of the Department of Pathology, SMSR, Sharda University.
Methods: Retrospective analysis of 27 complete blood counts and peripheral blood smears of neonates was conducted over one month. Smears had been prepared and stored for examination, and reports had been dispatched. Clinical details (As available from clinicians), parameters for neonatal sepsis (NLR, PLR, IG), platelet counts, and nRBC counts were recorded and tabulated. For result tabulation, neonatal samples were divided into two groups: 0-1 day and 2-30 days.
Results: The neonates included 17 males and 9 females. Assessment of NLR, PLR, and IG indicated higher values in the 2-30-day group compared to the 0-1-day group. Moreover, nRBCs were also elevated in the 2-30-day group.
Conclusion: The presence of nRBCs in peripheral blood smears is an important indicator of neonatal stress, including sepsis, jaundice, and hypoxic sepsis.
