Showing 8 results for nazari
Nazari, H, Habibeh Najar, H, Emadi, A, Abasi, Y, Salehiyan, A, Monem, M, Ghods, F, Mohammadi, A., Khaleghian, A,
Volume 5, Issue 2 (Autumn – Winter 2011[PERSIAN] 2011)
Abstract
Abstract Background and objectives: Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway. G6PD deficiency (an X-linked recessive hereditary disease) is an inherited condition affecting approximately 3% of the people globally. This deficiency can cause hemolytic anemia and jaundice in neonates. The goal of this study is to detect the prevalence of G6PD deficiency in neonates referred to Semnan province screening lab Material and Methods: This cross sectional study, from 2007 to 2010, was conducted on the basis of country planned program and in line with neonatal screening tests. Blood samples were taken from the heels of 3-5 day neonates. Assessment of G6PD was done by rapid fluorescent spot test. The Prevalence of G6PD deficiency in boys and girls was compared by chi square (p<0.05(test. Results: Of 9353 newborns referred to semnan province screening Lab., 4820(51.53%) are males and 4533(48.47%) females. Three hundred (3.2%) of them suffer from G6PD deficiency. Of these, 263 (5.45%) are males and 37 (0.81%) females. The ratio of male to female is 7 to 1. Conclusion: The prevalence of G6PD deficiency is detected 3.2% in Semnan province and its frequency in boys is more than that of girls, which is expected. Key words: Glucose -6-phosphate dehydrogenase, Neonatal screening, Fauvism
A Mikaeili, Kh Rahmati,, A Ebrahimi, N Nazari,
Volume 7, Issue 4 (winter[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Superficial mycoses are increasing in special conditions. This retrospective study was conducted to determine the epidemiological parameters of Pityriasis versicolor and Erythrasma during 1994 – 2011.
Material and Methods: In this study, we assessed the results of direct microscopic study and the other data of the patients for Pityriasis versicolor and Erythrasma in 1994 – 2011.
Results: Of 2265, 1294 (57%) suffered from pityriasis versicolor, who were mostly males (60%). The highest frequency was related to 20-29 year old and the lowest to 0-9. High school and university students were the most infected groups (33%), September was the most common period and the most common site of involvement was chest and abdomen. The people infected with Erythrasma (971 42%), were mostly 30 -39 year old , males( 58% ) , urban ( 98% ) , reported in July and involved in groin.
Conclusion: The frequency of both diseases was high in active age group, males, and the hot months of the year, which are the most common predisposing factors.
Keywords: Pityriasis versicolor Erythrasma Kermanshah
R Esmaeili, Ma Amir-Zargar, M Nazari, M Alikhan,
Volume 7, Issue 5 (supplement Issue( Bacteriology)[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Urinary tract infections and bacteremia are the major problems in renal transplant patients, which are mostly due to immunesuppressive regimens, surgery, and exposure to the germs in hospital. The aim of this study was to determine the prevalence of bacterial agents in the blood and urine samples of kidney transplant candidates.
Material and Methods: In this one-year-long study, thirty-three renal transplant candidates were assessed for urine and blood cultures. One urine and blood samples from each patient before transplantation and three samples after transplantation were collected. The Samples, using standard microbiological methods, were investigated and infectious organisms identified.
Results: In 133 urine samples, Escherichia coli (20.5%), Enterobacter spp. (5.3%), Klebsiella spp. (3 %) and Staphylococcus epidermidis (1.5%) were isolated. In the blood samples, Enterobacter spp. (9.1%), Escherichia coli (6.8%), Staphylococcus epidermidis (3.8%) and Klebsiella spp. (0.8%) were isolated.
Conclusion: The results indicate that urinary tract infection was high in patients with transplanted kidney, and E. coli is the most common cause of this infection.
Keywords: Kidney Transplantation Bacterial infections Urinary Tract and Blood Infections Escherichia Coli
Z Nazari, E Tabarraei, J Akbarmehr,
Volume 8, Issue 1 (spring[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Respiratory tract infections (RTI) are the most common infectious disorders, worldwide. About 80%-90% of RTI are caused by four viruses such as Adenoviruses, 51 serotypes have been introduced so far. The aim of this survey was to evaluate the frequency of Adenovirus in respiratory infected patients by PCR method in Golestan province, Iran.
Material and Methods: This descriptive cross-sectional study was conducted on 400 patients with clinical diagnosis of flu-like respiratory infection, 2010-2012. In addition to collecting demographic and clinical data, nasopharyngeal swabs were taken and transferred to the virology laboratory in viral transport medium (VTM), and evaluated by PCR method for Adenovirus after genomic extraction. Using SPSS v.11 software, we analyzed the data.
Results: Thirty-seven (9.2 %) were positive for Adenovirus. No significant correlation was found between being positive for Adenovirus and the variables such as age, gender and season. Clinical signs were coughing (27 73%), body pain (25 67.6%), and fever (24 64.9%). Thirty-five of the patients (94.5%) had at least one symptom.
Conclusion: Our findings are consistent with other research conducted in Iran and other countries. There is a significant correlation between Adenovirus infection and clinical symptoms.
Keywords: Respiratory Infection, Adenovirus, PCR, Golestan, Iran
N Nazari, Ma Rahimi, E Bayat,
Volume 8, Issue 3 (Autumn[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Trichomonas vaginalis is a pathogenic agent known worldwide and affects about 180 million annually. We aimed to investigate the prevalence of Trichomonas vaginalis in diabetic patients referred to diabetic research center.
Material and Methods: In this descriptive-analytic study, 215 women referring to the Diabetic Center in Kermanshah Province were investigated for Trichomonas vaginalis. After collecting the data by a questionnaire, the samples were obtained from posterior fornix by sterile swabs and sent for assessing by direct microscopy and Dorset medium.
Results: Totally, 1.3 percent of the women were confirmed to be infected with T. vaginalis.
Conclusion: The range of blood sugar cannot remarkably affect the prevalence of T. vaginalis. Given the limitations of this study and low prevalence compared to similar studies, we recommend further comprehensive research for better understanding.
Keywords: Trichomonas Vaginalis, Diabet, Prevalence
Farzad Nazem, Malihe Ardakani, Mohammad Reza Gholami, Kamal Ranjbar, Afshin Nazari,
Volume 10, Issue 5 (Sep-Oct-2016 2016)
Abstract
ABSTRACT
Background and Objective: Scientific evidence reveals that the density of skeletal muscle microcirculations decreases in the patients with chronic heart failure. Therefore, this study aimed to determine the impact of submaximal aerobic exercise training on restoration of fast/slow-twitch muscle fibers microcirculation in rats with myocardial infarction.
Methods: In this experimental study, 30 male infarcted Wistar rats were randomly divided into three groups of sham (N=10), control (N=10) and exercise (N=10), four weeks after surgery (blockage of anterior descending artery). Daily aerobic exercise included running on a treadmill for 10 weeks (5 times a week) at a speed of 17 m/min within 10 to 50 minutes. The animals were anesthetized and then sacrificed with chloroform, 48 hours after the last training session. The microcirculation density of soleus (SOL) and gastrocnemius (Gw) muscles was evaluated by immunohistochemistry assay.
Results: Capillary density and capillary to SOL muscle fiber ratio significantly increased in response to exercise training. However, capillary density, capillary to Gw muscle fiber ratio and Gw muscle arteriolar density of Wistar rats with chronic heart failure were not significantly affected by the exercise program. Moreover, arteriolar density of Gw muscle increased significantly after the exercise program.
Conclusion: The ten-week aerobic exercise might non-uniformly improve the SOL and Gw muscles microcirculation in rats with chronic heart failure by increasing capillary density and capillary to fiber ratio in the SOL muscle and increasing the arteriolar density of the Gw muscle.
Keywords: Heart Failure, Angiogenesis, Exercise.
Zeinab Nazari, Javad Ghaffari, Negar Ghaffari,
Volume 14, Issue 3 (May-Jun 2020)
Abstract
Background and Objectives: Human T lymphotropic virus type I (HTLV-I) is a virus of the Retroviridae family, which has infected more than 20 million people around the world. The study aimed to review the prevalence of HTLV infection in pregnant women.
Methods: We searched various databases including PubMed, EMBASE, Scopus, Google Scholar, SID, Magiran and Irandoc using the following keywords: HTLV-1, HTLV-2, Retroviridae, pregnancy, prevalence, incidence, women and female. Abstracts, short/brief reports as well as original and review articles published on HTLV-1 and/or HTLV-2 infection during pregnancy until October 2018 were included in the study.
Results: We found five articles from Iran and 14 articles from other parts of the world on the prevalence of HTLV-1 infection in pregnant women. Prevalence of HTLV-1 and or HTLV-2 was higher in pregnant women than in non-pregnant women in cities of Mashhad and Neyshabur, Razavi Khorasan Province (1.5 to 3.3 %), northeastern Iran, which are endemic areas of Iran for HTLV-1 infection. The incidence rate of HTLV-1 infection was 400-500 per 10,000 pregnant women in endemic areas of Japan. In Brazil, the rate of HTLV-1 infection in pregnant women was estimated to be 1.05%.
Conclusion: The prevalence of HTLV-1 varies among pregnant women depending on residence in endemic or non-endemic areas for HTLV-1. In endemic areas, it is recommended to perform routine screening for HTLV-1 infection in the general population, especially pregnant women.
Azadeh Abedzadeh Hajar, Mohammad Dakhili, Mojgan Saghazadeh, Seyyed Soheil Aghaei, Razieh Nazari,
Volume 14, Issue 3 (May-Jun 2020)
Abstract
Background and Objective: The prevalence of the infections caused by Candida species has led to a significant increase in their resistance to antifungal compounds. The aim of this study was to i) investigate drug resistance ii) evaluate the incidence of Candida albicans drug resistance pattern in the vaginal samples of women referring to health centers of Qom province, and iii) examine the effect of Zn nanoparticles combined with fluconazole against C. albicans isolates.
Methods: This experimental, descriptive study was performed on 120 patients of candidiasis. In order to identify Candida albicans, direct experiments, differential culture, Germ tube test and sugar assimilation test (API20C kit) were conducted. The effect of different antifungal drugs and zinc nanoparticles and the synergistic effect of fluconazole with zinc nanoparticles were investigated by disk diffusion method. Minimum Inhibitory Concentration (MICs) of all cases was further specified.
Results: Of the 120 samples, 50 (41.6%) were identified as Candida albicans. These strains were resistant to certain antifungal drugs while others were semi-sensitive and sensitive. The lowest and the highest mean diameter of inhibition zone in all Candida albicans isolates belonged to ketoconazole (15.64 mm) and fluconazole nano-ZnO (26.76mm), respectively. The lowest and the highest MICs were observed in fluconazole- nano-ZnO and nano-ZnO, respectively.
Conclusion: The synergistic effect of Zn nanoparticles with fluconazole can be conducive to the treatment of vaginal candidiasis.
