Showing 5 results for Risk Factors
Emam, S J., Asgari, M., Hosseini, S A., Shahbazian, H., Veisi, E., Vali, M., Latifi, S M., Malihi, R.,
Volume 6, Issue 2 (10-2012)
Abstract
Abstract
Background and objectives: Diabetes is a chronic and progressive disease resulting in disability and premature death. The Etiology of diabetes mellitus is complex, but factors such as genetic, immunological and environmental are involved .The aim of this study was to investigate the association between diabetes and blood type.
Material and Methods: In this cross - sectional study blood group of 500 patients with diabetes type 2 was determined and compared with the distribution of blood groups in 11,461 healthy people in Ahwaz. Statistical analysis was performed by independent T test, using SPSS Software (version 17)
Results: the Patients’ age is between 35 and 80 years. Their Blood groups are A (106 20.3 %) B (144 27.5%) AB (97 18.5%) and O (176 32.7%). One hundred seventy-nine (34.2%) cases are Rh+ and the rest (344 65.8 %) Rh- .
Conclusion: Regarding to the distribution of blood group AB and Rh- ,which respectively are 7.3% and 8.4%, the chance of developing diabetes in theses people is higher than that in other people (P<0.05). Hence, they should follow a healthy lifestyle from early years of life to reduce the risk of diabetes.
Key words: Diabetes type 2, blood group, risk factors
Mohamad Reza Nazer, Zia Obeidavi, Behrouz Beiranvand, Mahshid Garmsiri ,
Volume 10, Issue 5 (9-2016)
Abstract
ABSTRACT
Background and Objective: This study was conducted to evaluate epidemiology of risk factors for hepatitis C virus (HCV) transmission, and determine the association of its genotypes with viral load and response to treatment in patients referred to the Infectious Disease Clinic of Khorramabad.
Methods: The study included patients infected with hepatitis C referred to the Infectious Disease Clinic of Khorramabad during 2011-14. Those who met the inclusion criteria were referred to counseling centers for risky behaviors. After collecting demographic and epidemiologic data on the modes of transmission, blood samples were collected for more accurate testing. The erum of patients with hepatitis C was evaluated in terms of HCV genotype and viral load using PCR.
Results: Among 120 patients studied, 102 (85%) were male and 18 (15%) were female. The most prevalent genotypes were 3a (63.8%), 1a (25%), 1a/1b (5.2%) and 2 (1.7%). Intravenous drug abuse was the main route of transmission of hepatitis C in the study. The genotypes 3a and 1a had a clear correlation with intravenous drug abuse and history of blood transfusion (P<0.05). It was also found that the patients with genotype 3a show a better initial response to treatment with interferon.
Conclusion: The study shows that intravenous drug abuse is the main route of transmission, which highlights the need for intervention and education in this group of patients to prevent disease transmission.
Keywords: Hepatitis C, Genotype, Intravenous Drug Abuse, HIV, Interferon.
Behrouz Farhadihosseinabadi , Fahimeh Hosseini , Pegah Larki , Nader Bagheri , Kazem Abbaszadeh-Goudarzi , Koushan Sinehsepehr , Behrooz Johari , Meghdad Abdollahpour-Alitappeh ,
Volume 12, Issue 5 (9-2018)
Abstract
ABSTRACT
Breast cancer remains the most common cancer of women and one of the most common causes of cancer-related deaths worldwide. In spite of major advances in breast cancer diagnosis and treatment, the incidence of breast cancer remains high and the treatment of metastatic breast cancer remains challenging. This review presents an overview of breast cancer with a particular focus on its clinical aspects and therapies.
Keywords: Breast Cancer, Risk Factors, Diagnosis, Treatment.
Ameneh Arab, Alireza Mohebbi, Hamid Afshar, Abdolvahab Moradi,
Volume 12, Issue 5 (9-2018)
Abstract
ABSTRACT
Background and Objectives: Psychiatric disorders such as schizophrenia and bipolar disorder pose a high burden among the general population. Etiological factor(s) of such disorders remain unknown. Borna disease virus (BDV) is a neurotropic virus that has been suggested as an etiological agent for psychiatric disorders. Therefore, we aimed to investigate the prevalence of BDV among patients with schizophrenia and bipolar disorder.
Methods: Peripheral blood mononuclear cells (PBMCs) of schizophrenic (n=75) and bipolar (n=55) patients and healthy blood donors (n=125) were extracted form whole blood samples. RNA was extracted from PBMCs and the presence of BDV P40 RNA was assessed by reverse transcription-polymerase chain reaction.
Results: The BDV genome was not detected in any of the subjects. Positive family history of disease was significantly more frequent among patients (P=0.0001). There was a significant association between contact with animals and psychiatric illnesses (P<0.05). Moreover, education level differed significantly between the two groups (P<0.05).
Conclusion: The results indicate no evidence of BDV genome among patients with psychiatric disorders. Serological examination for BDV antigens or antibodies could provide further information in this regard. In addition, contact with cats is significantly more prevalent among patients with mental illnesses, which might be due to infection with Toxoplasma gondii.
Keywords: Borna disease virus, Psychiatric disorder, Schizophrenia, Bipolar disorder, Risk factors.
Minoo Dadban Shahamat, Asra Askari, Ramezan Arab Koohsar ,
Volume 15, Issue 2 (3-2021)
Abstract
Background and objectives: Elevated blood lipids and physical inactivity are known risk factors of atherosclerosis. The objective of this study was to compare effects of four weeks of high-intensity intermittent training (HIIT) and continuous walking on atherogenic indices of obese middle-aged men.
Methods: Study population consisted of 36 male teachers aged 35-50 years, with mean body mass index (BMI) of 30.7 ± 3.5 kg/m2 who were working in the city of Galikesh, northeastern Iran. The subjects were enrolled via purposeful sampling and were randomly divided into two experimental groups and a control group. Before and after the intervention, anthropometric characteristics (height, weight and BMI) and blood pressure of each subject were measured. Fasting blood samples were taken from the left brachial vein 12 hours before the first exercise session and 12 hours after the last exercise session to determine lipid profile. Data were analyzed using SPSS 18 at significance level of 0.05.
Results: The four-week walking exercise significantly decreased serum levels of low-density lipoprotein-cholesterol (LDL-C) (P=0.001) and triglyceride (P=0.001). In addition, the HIIT program significantly increased high-density lipoprotein level (HDL-C) (P=0.004) and significantly reduced LDL-C (P=0.049), LDL/HDL (P=0.002), triglyceride (p=0.01), BMI (P=0.027) and blood pressure (P=0.002). In addition, the results of ANOVA and (Scheffe test) showed a significant increase in HDL-C (P=0.042) values and a significant decrease in VLDL-C (P=0.032), LDL/HDL (P=0.041), triglyceride (P=0.024), BMI (P=0.048) and blood pressure (P=0.016) of HIIT group compared to the control group.
Conclusion: Our findings indicated that HIIT has beneficial effects on some risk factors of atherosclerosis and cardiovascular disease.
